How it works
- 1Paste one SMILES per line. Standard .smi lines such as “CCO ethanol” are supported.
- 2Run the conversion locally.
- 3Download one result, a combined file, or all results as ZIP.
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BROWSER · sci-form WASM + Toolardo chemical conversion core
SMILES to SDF Converter
Convert single or bulk SMILES to 3D SDF files locally in your browser, then download combined SDF or ZIP.
✓ Single and bulk conversion✓ Runs locally in your browser✓ Combined output and ZIP download
Input
Single + BulkChoose one or more files
A 3D conformer is generated because SMILES has no coordinates. The original SMILES is stored as an SDF property; downstream protonation/stereochemistry requirements should still be checked.
Molecular data are processed locally in your browser.
Results
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0Success
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About this tool
Convert single or bulk SMILES to 3D SDF files locally in your browser, then download combined SDF or ZIP.
Common uses
SMILES to SDFbulk smiles to sdf converterconvert smiles to sdfturn smiles into sdf
Frequently asked questions
Are my molecular files uploaded?
No. Conversion runs locally in your browser. The SMILES 3D engine code is loaded as a browser dependency, but your molecular input is not sent to Toolardo.
Does conversion preserve every property from the source format?
A 3D conformer is generated because SMILES has no coordinates. The original SMILES is stored as an SDF property; downstream protonation/stereochemistry requirements should still be checked.